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Biomarker Genes Discovery of Alzheimer’s Disease by Multi-Omics-Based Gene Regulatory Network Construction of Microglia

Microglia, the major immune cells in the brain, mediate neuroinflammation, increased oxidative stress, and impaired neurotransmission in Alzheimer’s disease (AD), in which most AD risk genes are highly expressed. In microglia, due to the limitations of current single-omics data analysis, risk genes,...

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Detalles Bibliográficos
Autores principales: Gao, Wenliang, Kong, Wei, Wang, Shuaiqun, Wen, Gen, Yu, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496783/
https://www.ncbi.nlm.nih.gov/pubmed/36138932
http://dx.doi.org/10.3390/brainsci12091196