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Biomarker Genes Discovery of Alzheimer’s Disease by Multi-Omics-Based Gene Regulatory Network Construction of Microglia
Microglia, the major immune cells in the brain, mediate neuroinflammation, increased oxidative stress, and impaired neurotransmission in Alzheimer’s disease (AD), in which most AD risk genes are highly expressed. In microglia, due to the limitations of current single-omics data analysis, risk genes,...
Autores principales: | Gao, Wenliang, Kong, Wei, Wang, Shuaiqun, Wen, Gen, Yu, Yaling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496783/ https://www.ncbi.nlm.nih.gov/pubmed/36138932 http://dx.doi.org/10.3390/brainsci12091196 |
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