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In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity

SIMPLE SUMMARY: Prostate cancer is diagnosed in one out of eight men, with large implications on life quality. Forkhead box proteins are often found mutated in prostate cancer but their functions are still not fully understood. In this study, we applied CRISPR to investigate the function of two Fork...

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Detalles Bibliográficos
Autores principales: Cai, Huiqiang, Agersnap, Simon N., Sjøgren, Amalie, Simonsen, Mikkel K., Blaavand, Mathilde S., Jensen, Ulrikke V., Thomsen, Martin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496785/
https://www.ncbi.nlm.nih.gov/pubmed/36139541
http://dx.doi.org/10.3390/cancers14184381