Cargando…
In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity
SIMPLE SUMMARY: Prostate cancer is diagnosed in one out of eight men, with large implications on life quality. Forkhead box proteins are often found mutated in prostate cancer but their functions are still not fully understood. In this study, we applied CRISPR to investigate the function of two Fork...
Autores principales: | Cai, Huiqiang, Agersnap, Simon N., Sjøgren, Amalie, Simonsen, Mikkel K., Blaavand, Mathilde S., Jensen, Ulrikke V., Thomsen, Martin K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496785/ https://www.ncbi.nlm.nih.gov/pubmed/36139541 http://dx.doi.org/10.3390/cancers14184381 |
Ejemplares similares
-
Targeting AP-1 transcription factors by CRISPR in the prostate
por: Riedel, Maria, et al.
Publicado: (2021) -
The CRISPR/Cas9 Minipig—A Transgenic Minipig to Produce Specific Mutations in Designated Tissues
por: Berthelsen, Martin Fogtmann, et al.
Publicado: (2021) -
Foxa1 and Foxa2 Are Required for Formation of the Intervertebral Discs
por: Maier, Jennifer A., et al.
Publicado: (2013) -
CRISPR/Cas9-Mediated Foxp1 Silencing Restores Immune Surveillance in an Immunocompetent A20 Lymphoma Model
por: Felce, Suet Ling, et al.
Publicado: (2020) -
FOXA1 in prostate cancer
por: Dong, Hui-Yu, et al.
Publicado: (2022)