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White Paper: Mimetics of Class 2 Tumor Suppressor Proteins as Novel Drug Candidates for Personalized Cancer Therapy

SIMPLE SUMMARY: A concept is presented for a new therapeutic approach, still in its early stages, which focuses on the phenotypic mimicry (“mimesis”) of proteins encoded by highly disease-relevant class 2 tumor suppressor genes that are silenced by DNA promoter methylation. Proteins derived from tum...

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Detalles Bibliográficos
Autores principales: Dahl, Edgar, Villwock, Sophia, Habenberger, Peter, Choidas, Axel, Rose, Michael, Klebl, Bert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496810/
https://www.ncbi.nlm.nih.gov/pubmed/36139547
http://dx.doi.org/10.3390/cancers14184386