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SPHK/HIF-1α Signaling Pathway Has a Critical Role in Chrysin-Induced Anticancer Activity in Hypoxia-Induced PC-3 Cells

Hypoxia, a typical feature of locally advanced solid tumors including prostate cancer, is a critical contributor to tumor progression and causes resistance to therapy. In this study, we investigated the effects of chrysin on tumor progression in hypoxic PC-3 cells. Chrysin exerted a significant inhi...

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Detalles Bibliográficos
Autores principales: Han, Hengmin, Lee, Seon-Ok, Xu, Yinzhu, Kim, Jung-Eun, Lee, Hyo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496844/
https://www.ncbi.nlm.nih.gov/pubmed/36139362
http://dx.doi.org/10.3390/cells11182787