Systematic Analysis of Genetic and Pathway Determinants of Eribulin Sensitivity across 100 Human Cancer Cell Lines from the Cancer Cell Line Encyclopedia (CCLE)

SIMPLE SUMMARY: Despite decades of clinical use and detailed understandings of their mechanisms of action, clinically useful predictive biomarkers for approved microtubule targeting agents such as eribulin, paclitaxel and vinorelbine have eluded development. Our results now provide the basis for gen...

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Detalles Bibliográficos
Autores principales: Sachdev, Pallavi, Ronen, Roy, Dutkowski, Janusz, Littlefield, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496846/
https://www.ncbi.nlm.nih.gov/pubmed/36139690
http://dx.doi.org/10.3390/cancers14184532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496846/
https://www.ncbi.nlm.nih.gov/pubmed/36139690
http://dx.doi.org/10.3390/cancers14184532

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