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Augmented Antitumor Effect of Unripe Rubus coreanus Miquel Combined with Oxaliplatin in a Humanized PD-1/PD-L1 Knock-In Colorectal Cancer Mouse Model

Immune checkpoint inhibitors (ICIs) have been shown to be extraordinarily effective in patients with colorectal cancer (CRC). However, the current ICIs still have adverse effects and limited efficacy of ICI monotherapy. We used a natural product to overcome the vulnerability of ICIs and tried a comb...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Ji, Yang, Ju-Hye, Choi, Jang-Gi, Chung, Hwan-Suck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496898/
https://www.ncbi.nlm.nih.gov/pubmed/36139451
http://dx.doi.org/10.3390/cells11182876