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SARS-CoV-2 Infection of Airway Epithelium Triggers Pulmonary Endothelial Cell Activation and Senescence Associated with Type I IFN Production

Airway epithelial cells represent the main target of SARS-CoV-2 replication but several pieces of evidence suggest that endothelial cells (ECs), lining pulmonary blood vessels, are key players in lung injury in COVID-19 patients. Although in vivo evidence of SARS-CoV-2 affecting the vascular endothe...

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Detalles Bibliográficos
Autores principales: Bordoni, Veronica, Mariotti, Davide, Matusali, Giulia, Colavita, Francesca, Cimini, Eleonora, Ippolito, Giuseppe, Agrati, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496907/
https://www.ncbi.nlm.nih.gov/pubmed/36139488
http://dx.doi.org/10.3390/cells11182912