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Melatonin Attenuates Spinal Cord Injury in Mice by Activating the Nrf2/ARE Signaling Pathway to Inhibit the NLRP3 Inflammasome

Background: Spinal cord injury (SCI) is a central nervous system (CNS) trauma involving inflammation and oxidative stress, which play important roles in this trauma’s pathogenesis. Therefore, controlling inflammation is an effective strategy for SCI treatment. As a hormone, melatonin is capable of p...

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Detalles Bibliográficos
Autores principales: Wang, Haoyu, Wang, Haifan, Huang, Heng, Qu, Zhigang, Ma, Dong, Dang, Xiaoqian, Dong, Quanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496911/
https://www.ncbi.nlm.nih.gov/pubmed/36139384
http://dx.doi.org/10.3390/cells11182809