Enhanced Antitumoral Activity of Encapsulated BET Inhibitors When Combined with PARP Inhibitors for the Treatment of Triple-Negative Breast and Ovarian Cancers

SIMPLE SUMMARY: Poly (adenosine diphosphate ribose) polymerase inhibitors (PARPis) have demonstrated antitumoral activity in several cancers harbouring germline and somatic BRCA1/2 mutations. The widespread use of these agents in clinical practice is restricted by the development of acquired resista...

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Detalles Bibliográficos
Autores principales: Juan, Alberto, Noblejas-López, María del Mar, Bravo, Iván, Arenas-Moreira, María, Blasco-Navarro, Cristina, Clemente-Casares, Pilar, Lara-Sánchez, Agustín, Pandiella, Atanasio, Alonso-Moreno, Carlos, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496913/
https://www.ncbi.nlm.nih.gov/pubmed/36139634
http://dx.doi.org/10.3390/cancers14184474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496913/
https://www.ncbi.nlm.nih.gov/pubmed/36139634
http://dx.doi.org/10.3390/cancers14184474

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