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CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B

(1) Background: The lack of specific targets has slowed the progress of CAR-T in treating solid tumors. Recent studies have revealed that EDB-FN (fibronectin extra domain B) may be an effective target for CAR-T treatment of solid tumors; EDB-FN is expressed in tumor and embryonic tissues, and antibo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhijie, Liu, Chang, Yang, Zhe, Yin, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496916/
https://www.ncbi.nlm.nih.gov/pubmed/36139437
http://dx.doi.org/10.3390/cells11182863