Anti-PTK7 Monoclonal Antibodies Inhibit Angiogenesis by Suppressing PTK7 Function

SIMPLE SUMMARY: PTK7 is a catalytically defective receptor protein tyrosine kinase. We previously demonstrated that PTK7 enhances angiogenesis by interacting with KDR, a vascular endothelial growth factor (VEGF) receptor important for angiogenesis, and activating it through oligomerization. To contr...

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Detalles Bibliográficos
Autores principales: Oh, Si Won, Shin, Won-Sik, Lee, Seung-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496920/
https://www.ncbi.nlm.nih.gov/pubmed/36139622
http://dx.doi.org/10.3390/cancers14184463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496920/
https://www.ncbi.nlm.nih.gov/pubmed/36139622
http://dx.doi.org/10.3390/cancers14184463

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