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Anti-PTK7 Monoclonal Antibodies Inhibit Angiogenesis by Suppressing PTK7 Function

SIMPLE SUMMARY: PTK7 is a catalytically defective receptor protein tyrosine kinase. We previously demonstrated that PTK7 enhances angiogenesis by interacting with KDR, a vascular endothelial growth factor (VEGF) receptor important for angiogenesis, and activating it through oligomerization. To contr...

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Detalles Bibliográficos
Autores principales:	Oh, Si Won, Shin, Won-Sik, Lee, Seung-Taek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496920/ https://www.ncbi.nlm.nih.gov/pubmed/36139622 http://dx.doi.org/10.3390/cancers14184463

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