The Biological and Clinical Consequences of RNA Splicing Factor U2AF1 Mutation in Myeloid Malignancies

SIMPLE SUMMARY: U2 small nuclear RNA auxiliary factor 1 (U2AF1) is one of the most important RNA splicing genes involved in regulating the alternative splicing of pre-mRNA. U2AF1 mutation is a genetic driver event in the initiation of myelodysplastic syndromes (MDSs) and frequently occurs in myeloid...

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Detalles Bibliográficos
Autores principales: Zhao, Yangjing, Cai, Weili, Hua, Ye, Yang, Xiaochen, Zhou, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496927/
https://www.ncbi.nlm.nih.gov/pubmed/36139566
http://dx.doi.org/10.3390/cancers14184406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496927/
https://www.ncbi.nlm.nih.gov/pubmed/36139566
http://dx.doi.org/10.3390/cancers14184406

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