Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome

Parkinson’s disease (PD) is a common age-associated neurodegenerative motor disorder, which is mainly caused by dopaminergic neuron loss in the substantia nigra. This study aimed to evaluate the function and the underlying molecular mechanism of itaconate in PD. PD models were established in vivo an...

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Detalles Bibliográficos
Autores principales: Sun, Guoqing, Zhang, Rui, Liu, Chengxiao, Meng, Wenjun, Pang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496935/
https://www.ncbi.nlm.nih.gov/pubmed/36138991
http://dx.doi.org/10.3390/brainsci12091255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496935/
https://www.ncbi.nlm.nih.gov/pubmed/36138991
http://dx.doi.org/10.3390/brainsci12091255

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