Molecular Divergence upon EGFR-TKI Resistance Could Be Dependent on the Exon Location of the Original EGFR-Sensitizing Mutation

SIMPLE SUMMARY: In this study, we report that the exon location of the original EGFR-sensitizing mutation could drive resistance mechanisms underlying tumor progression in advanced EGFR-positive NSCLC patients under targeted therapies. In our study, plasma detection of the p.T790M EGFR resistance mu...

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Detalles Bibliográficos
Autores principales: Serna-Blasco, Roberto, Sánchez-Herrero, Estela, Robado de Lope, Lucía, Sanz-Moreno, Sandra, Rodríguez-Festa, Alejandro, Ares-Trotta, Dunixe, Cruz-Bermúdez, Alberto, Franco, Fabio, Sánchez-Hernández, Alfredo, Campayo, María de Julián, García-Girón, Carlos, Dómine, Manuel, Blasco, Ana, Sánchez, José M., Oramas, Juana, Bosch-Barrera, Joaquim, Sala, María Á., Sereno, María, Romero, Atocha, Provencio, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496947/
https://www.ncbi.nlm.nih.gov/pubmed/36139605
http://dx.doi.org/10.3390/cancers14184446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496947/
https://www.ncbi.nlm.nih.gov/pubmed/36139605
http://dx.doi.org/10.3390/cancers14184446

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