Effects of Elamipretide on Autophagy in Renal Cells of Pigs with Metabolic Syndrome

Autophagy eliminates excessive nutrients and maintains homeostasis. Obesity and metabolic syndrome (MetS) dysregulate autophagy, possibly partly due to mitochondria injury and inflammation. Elamipretide (ELAM) improves mitochondrial function. We hypothesized that MetS blunts kidney autophagy, which...

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Detalles Bibliográficos
Autores principales: Hong, Siting, Ghandriz, Ramyar, Siddiqi, Sarosh, Zhu, Xiang-Yang, Saadiq, Ishran M., Jordan, Kyra L., Tang, Hui, Ali, Khaled A., Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496989/
https://www.ncbi.nlm.nih.gov/pubmed/36139466
http://dx.doi.org/10.3390/cells11182891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496989/
https://www.ncbi.nlm.nih.gov/pubmed/36139466
http://dx.doi.org/10.3390/cells11182891

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