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Androgen Receptor Splice Variants Contribute to the Upregulation of DNA Repair in Prostate Cancer

SIMPLE SUMMARY: Ligand-independent androgen receptor splice variants emerge during androgen deprivation therapy and are suspected to render prostate carcinomas castration-resistant. In a retrospective analysis of a large cohort of primary and advanced prostate tumors, we observed increased expressio...

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Detalles Bibliográficos
Autores principales: Tolkach, Yuri, Kremer, Anika, Lotz, Gábor, Schmid, Matthias, Mayr, Thomas, Förster, Sarah, Garbe, Stephan, Hosni, Sana, Cronauer, Marcus V., Kocsmár, Ildikó, Kocsmár, Éva, Riesz, Péter, Alajati, Abdullah, Ritter, Manuel, Ellinger, Jörg, Ohlmann, Carsten-Henning, Kristiansen, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496991/
https://www.ncbi.nlm.nih.gov/pubmed/36139600
http://dx.doi.org/10.3390/cancers14184441