Inhibition of KRAS, MEK and PI3K Demonstrate Synergistic Anti-Tumor Effects in Pancreatic Ductal Adenocarcinoma Cell Lines

SIMPLE SUMMARY: Small molecule inhibitors and targeted therapy are considered to have significant potential for pancreatic ductal adenocarcinoma therapies. Preclinical studies of novel inhibitors and inhibitor combinations can elucidate their acting mechanisms and provide valuable data for in vivo r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yixuan, Schulz, Benjamin, Trakooljul, Nares, Al Ammar, Moosheer, Sekora, Anett, Sender, Sina, Hadlich, Frieder, Zechner, Dietmar, Weiss, Frank Ulrich, Lerch, Markus M., Jaster, Robert, Junghanss, Christian, Murua Escobar, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497071/
https://www.ncbi.nlm.nih.gov/pubmed/36139627
http://dx.doi.org/10.3390/cancers14184467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497071/
https://www.ncbi.nlm.nih.gov/pubmed/36139627
http://dx.doi.org/10.3390/cancers14184467

Ejemplares similares