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Downregulation of the Tumor Suppressor TFF1 Is Required during Induction of Colon Cancer Progression by L1

SIMPLE SUMMARY: Aberrant activation of Wnt/β-catenin signaling and the subsequent induction of downstream target genes is a hallmark of colorectal cancer (CRC) development. Previously, we found that overexpression of the immunoglobulin-like cell adhesion receptor L1CAM (L1), a target of the Wnt/β-ca...

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Detalles Bibliográficos
Autores principales: Saha, Arka, Gavert, Nancy, Brabletz, Thomas, Ben-Ze’ev, Avri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497096/
https://www.ncbi.nlm.nih.gov/pubmed/36139637
http://dx.doi.org/10.3390/cancers14184478