Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance

SIMPLE SUMMARY: Besides zinc, also iron and copper need to be considered to play a role in the mode of action and resistance development of the anticancer thiosemicarbazone COTI-2 and its derivatives. One of these derivatives (COTI-NMe(2)) was discovered as an interesting new drug candidate with imp...

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Detalles Bibliográficos
Autores principales: Pósa, Vivien, Stefanelli, Alessia, Nunes, Julia H. Bormio, Hager, Sonja, Mathuber, Marlene, May, Nóra V., Berger, Walter, Keppler, Bernhard K., Kowol, Christian R., Enyedy, Éva A., Heffeter, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497102/
https://www.ncbi.nlm.nih.gov/pubmed/36139615
http://dx.doi.org/10.3390/cancers14184455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497102/
https://www.ncbi.nlm.nih.gov/pubmed/36139615
http://dx.doi.org/10.3390/cancers14184455

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