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Differential DNA Methylation of THOR and hTAPAS in the Regulation of hTERT and the Diagnosis of Cancer

SIMPLE SUMMARY: Because of its high prevalence of >45% in 9 out of 11 (82%) cancer types screened, THOR hypermethylation has been suggested to be a frequent telomerase-activating mechanism in hTERT-expressing tumor types, e.g., in cancers of the prostate, breast, blood, colon, lung, bladder, and...

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Detalles Bibliográficos
Autores principales: Ott, Pauline, Araúzo-Bravo, Marcos J., Hoffmann, Michèle J., Poyet, Cedric, Bendhack, Marcelo L., Santourlidis, Simeon, Erichsen, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497117/
https://www.ncbi.nlm.nih.gov/pubmed/36139544
http://dx.doi.org/10.3390/cancers14184384