Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model

The purpose of this study was to investigate the role of sphingosine kinase 1 (SphK1), which generates sphingosine-1-phosphate (S1P), in corneal neovascularization (NV). Wild-type (WT) and Sphk1 knockout (Sphk1(−/−)) mice received corneal alkali-burn treatment to induce corneal NV by placing a 2 mm...

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Detalles Bibliográficos
Autores principales: Wilkerson, Joseph L., Basu, Sandip K., Stiles, Megan A., Prislovsky, Amanda, Grambergs, Richard C., Nicholas, Sarah E., Karamichos, Dimitrios, Allegood, Jeremy C., Proia, Richard L., Mandal, Nawajes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497123/
https://www.ncbi.nlm.nih.gov/pubmed/36139489
http://dx.doi.org/10.3390/cells11182914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497123/
https://www.ncbi.nlm.nih.gov/pubmed/36139489
http://dx.doi.org/10.3390/cells11182914

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