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Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer’s Disease Cohort

Background: The APOE4 allele is a genetic risk factor for developing late-onset Alzheimer’s disease (AD). Previous work by our group revealed that female APOE4 homozygotes with Lewy body (LB) pathology were more likely to experience psychosis compared to female APOE4 non-carriers, whereas in males t...

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Detalles Bibliográficos
Autores principales: Valcic, Mila, Khoury, Marc A., Kim, Julia, Fornazzari, Luis, Churchill, Nathan W., Ismail, Zahinoor, De Luca, Vincenzo, Tsuang, Debby, Schweizer, Tom A., Munoz, David G., Fischer, Corinne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497154/
https://www.ncbi.nlm.nih.gov/pubmed/36139002
http://dx.doi.org/10.3390/brainsci12091266