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Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis

Genetic variants in transmembrane 6 superfamily member 2 (TM6SF2), such as E167K, are associated with atherosclerotic cardiovascular disease (ASCVD). Chronic inflammation and lipid-laden macrophage foam cell formation are the central pathogeneses in the development of atherosclerosis. This study was...

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Detalles Bibliográficos
Autores principales: Zhu, Wenzhen, Liang, Wenying, Lu, Haocheng, Chang, Lin, Zhang, Jifeng, Chen, Y. Eugene, Guo, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497156/
https://www.ncbi.nlm.nih.gov/pubmed/36139452
http://dx.doi.org/10.3390/cells11182877