Cargando…
Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis
Genetic variants in transmembrane 6 superfamily member 2 (TM6SF2), such as E167K, are associated with atherosclerotic cardiovascular disease (ASCVD). Chronic inflammation and lipid-laden macrophage foam cell formation are the central pathogeneses in the development of atherosclerosis. This study was...
Autores principales: | Zhu, Wenzhen, Liang, Wenying, Lu, Haocheng, Chang, Lin, Zhang, Jifeng, Chen, Y. Eugene, Guo, Yanhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497156/ https://www.ncbi.nlm.nih.gov/pubmed/36139452 http://dx.doi.org/10.3390/cells11182877 |
Ejemplares similares
-
Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
por: Fan, Yanbo, et al.
Publicado: (2021) -
Three Members of Transmembrane-4-Superfamily, TM4SF1, TM4SF4, and TM4SF5, as Emerging Anticancer Molecular Targets against Cancer Phenotypes and Chemoresistance
por: Rahim, Nur Syafiqah, et al.
Publicado: (2023) -
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
por: Holmen, Oddgeir L., et al.
Publicado: (2014) -
Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma
por: Chen, Zhouxun, et al.
Publicado: (2011) -
Mechanism and therapeutic strategy of hepatic TM6SF2-deficient non-alcoholic fatty liver diseases via in vivo and in vitro experiments
por: Li, Zu-Yin, et al.
Publicado: (2022)