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Intermittent Hypoxia Interferes with Autocrine Effects of GABA on Insulin Secretion in Postnatal Rodents—Implications for Pediatric Obstructive Sleep Apnea

Gamma-amino butyric acid (GABA) is well known to help elevate pancreatic β cell vitality and insulin levels in blood. GABA works via a coupling with GABA receptors; thus, the concentration of GABA(A) receptors on the plasma membrane of β cells appears to be critical for insulin regulation. Various m...

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Detalles Bibliográficos
Autores principales: Pae, Eung-Kwon, Chung, Man-Kyo, Harper, Ronald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497165/
https://www.ncbi.nlm.nih.gov/pubmed/36138614
http://dx.doi.org/10.3390/children9091305