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Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy

Diabetic retinopathy (DR) is a serious complication of diabetes that results from sustained hyperglycemia, hyperlipidemia, and oxidative stress. Under these conditions, inducible nitric oxide synthase (iNOS) expression is upregulated in the macrophages (MΦ) and microglia, resulting in increased prod...

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Detalles Bibliográficos
Autores principales: Abdelrahman, Ammar A., Bunch, Katharine L., Sandow, Porsche V., Cheng, Paul N-M, Caldwell, Ruth B., Caldwell, R. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497170/
https://www.ncbi.nlm.nih.gov/pubmed/36139465
http://dx.doi.org/10.3390/cells11182890