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Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy
Diabetic retinopathy (DR) is a serious complication of diabetes that results from sustained hyperglycemia, hyperlipidemia, and oxidative stress. Under these conditions, inducible nitric oxide synthase (iNOS) expression is upregulated in the macrophages (MΦ) and microglia, resulting in increased prod...
Autores principales: | Abdelrahman, Ammar A., Bunch, Katharine L., Sandow, Porsche V., Cheng, Paul N-M, Caldwell, Ruth B., Caldwell, R. William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497170/ https://www.ncbi.nlm.nih.gov/pubmed/36139465 http://dx.doi.org/10.3390/cells11182890 |
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