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Experimental Induction of Intracranial Aneurysms in Rats: A New Model Utilizing a Genetic Modification within the EDNRA Gene

The rupture of an intracranial aneurysm (IA) leads to life-threatening subarachnoid hemorrhage. Aside from well-established risk factors, recently published genome-wide association studies of IA revealed the strong association of a common variant near the endothelin receptor type A (EDNRA) gene with...

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Detalles Bibliográficos
Autores principales: Lampmann, Tim, Borger, Valeri, Konczalla, Jürgen, Gispert, Suzana, Auburger, Georg, Vatter, Hartmut, Güresir, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497172/
https://www.ncbi.nlm.nih.gov/pubmed/36138975
http://dx.doi.org/10.3390/brainsci12091239