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Computational Insights into the Sequence-Activity Relationships of the NGF(1–14) Peptide by Molecular Dynamics Simulations

The Nerve Growth Factor (NGF) belongs to the neurothrophins protein family involved in the survival of neurons in the nervous system. The interaction of NGF with its high-affinity receptor TrkA mediates different cellular pathways related to Alzheimer’s disease, pain, ocular dysfunction, and cancer....

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Detalles Bibliográficos
Autores principales: Vittorio, Serena, Manelfi, Candida, Gervasoni, Silvia, Beccari, Andrea R., Pedretti, Alessandro, Vistoli, Giulio, Talarico, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497175/
https://www.ncbi.nlm.nih.gov/pubmed/36139382
http://dx.doi.org/10.3390/cells11182808