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Computational Insights into the Sequence-Activity Relationships of the NGF(1–14) Peptide by Molecular Dynamics Simulations
The Nerve Growth Factor (NGF) belongs to the neurothrophins protein family involved in the survival of neurons in the nervous system. The interaction of NGF with its high-affinity receptor TrkA mediates different cellular pathways related to Alzheimer’s disease, pain, ocular dysfunction, and cancer....
Autores principales: | Vittorio, Serena, Manelfi, Candida, Gervasoni, Silvia, Beccari, Andrea R., Pedretti, Alessandro, Vistoli, Giulio, Talarico, Carmine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497175/ https://www.ncbi.nlm.nih.gov/pubmed/36139382 http://dx.doi.org/10.3390/cells11182808 |
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