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Association between ABCB1 rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults

Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. ABCB1 is a human gene that encodes P-glycoprotein, an ATP-dependent efflux pump that may influence the pharmacokinetics of delta-9-tetrahydrocannabinol (THC), the primary psychoact...

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Detalles Bibliográficos
Autores principales: Matheson, Justin, Zhang, Yollanda J., Brands, Bruna, Wickens, Christine M., Tiwari, Arun K., Zai, Clement C., Kennedy, James L., Le Foll, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497180/
https://www.ncbi.nlm.nih.gov/pubmed/36138925
http://dx.doi.org/10.3390/brainsci12091189