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Association between ABCB1 rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults
Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. ABCB1 is a human gene that encodes P-glycoprotein, an ATP-dependent efflux pump that may influence the pharmacokinetics of delta-9-tetrahydrocannabinol (THC), the primary psychoact...
Autores principales: | Matheson, Justin, Zhang, Yollanda J., Brands, Bruna, Wickens, Christine M., Tiwari, Arun K., Zai, Clement C., Kennedy, James L., Le Foll, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497180/ https://www.ncbi.nlm.nih.gov/pubmed/36138925 http://dx.doi.org/10.3390/brainsci12091189 |
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