Cargando…

Association between ABCB1 rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults

Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. ABCB1 is a human gene that encodes P-glycoprotein, an ATP-dependent efflux pump that may influence the pharmacokinetics of delta-9-tetrahydrocannabinol (THC), the primary psychoact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matheson, Justin, Zhang, Yollanda J., Brands, Bruna, Wickens, Christine M., Tiwari, Arun K., Zai, Clement C., Kennedy, James L., Le Foll, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497180/ https://www.ncbi.nlm.nih.gov/pubmed/36138925 http://dx.doi.org/10.3390/brainsci12091189

Ejemplares similares

Influence of Cannabinoid Receptor 1 Genetic Variants on the Subjective Effects of Smoked Cannabis
por: Murphy, Thomas, et al.
Publicado: (2021)

THC labeling on cannabis products: an experimental study of approaches for labeling THC servings on cannabis edibles
por: Goodman, Samantha, et al.
Publicado: (2022)

Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer
por: Afrin, Farjana, et al.
Publicado: (2020)

Differential inflammatory profile in the lungs of mice exposed to cannabis smoke with varying THC:CBD ratio
por: Haidar, Zahraa, et al.
Publicado: (2023)

Cannabis Legalization and Acute Harm From High Potency Cannabis Products: A Narrative Review and Recommendations for Public Health
por: Matheson, Justin, et al.
Publicado: (2020)

The Heart and Cannabis (THC) Cohort: Differences in Baseline Health and Behaviors by Cannabis Use
por: Keyhani, Salomeh, et al.
Publicado: (2022)

Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) induces less state anxiety than THC-dominant cannabis
por: Hutten, Nadia R. P. W., et al.
Publicado: (2022)

Cannabis for the Management of Cancer Symptoms: THC Version 2.0?
por: Guzmán, Manuel
Publicado: (2018)

Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication
por: Theunissen, Eef L., et al.
Publicado: (2011)

Potency and Therapeutic THC and CBD Ratios: U.S. Cannabis Markets Overshoot
por: Pennypacker, Sarah D., et al.
Publicado: (2022)

Pharmacokinetic and Safety Evaluation of Various Oral Doses of a Novel 1:20 THC:CBD Cannabis Herbal Extract in Dogs
por: Chicoine, Alan, et al.
Publicado: (2020)

Impacts of recreational cannabis legalization on use and harms: A narrative review of sex/gender differences
por: Matheson, Justin, et al.
Publicado: (2023)

A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives
por: McPartland, John M., et al.
Publicado: (2020)

Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users
por: Ramaekers, Johannes G., et al.
Publicado: (2010)

Indeterminacy of cannabis impairment and ∆(9)-tetrahydrocannabinol (∆(9)-THC) levels in blood and breath
por: Wurz, Gregory T., et al.
Publicado: (2022)

Uncomfortably high: Testing reveals inflated THC potency on retail Cannabis labels
por: Schwabe, Anna L., et al.
Publicado: (2023)

Do Cannabis Users Reduce Their THC Dosages When Using More Potent Cannabis Products? A Review
por: Leung, Janni, et al.
Publicado: (2021)

THC and CBD Fingerprinting of an Elite Cannabis Collection from Iran: Quantifying Diversity to Underpin Future Cannabis Breeding
por: Mostafaei Dehnavi, Mahboubeh, et al.
Publicado: (2022)

The frequency distribution of reported THC concentrations of legal cannabis flower products increases discontinuously around the 20% THC threshold in Nevada and Washington state
por: Zoorob, Michael J.
Publicado: (2021)

Oral Administration of Cannabis and Δ-9-tetrahydrocannabinol (THC) Preparations: A Systematic Review
por: Poyatos, Lourdes, et al.
Publicado: (2020)

Cannabis sativa: Interdisciplinary Strategies and Avenues for Medical and Commercial Progression Outside of CBD and THC
por: Oultram, Jackson M. J., et al.
Publicado: (2021)

Analysis of Anti-Cancer and Anti-Inflammatory Properties of 25 High-THC Cannabis Extracts
por: Li, Dongping, et al.
Publicado: (2022)

Sex Differences in the Neuropsychiatric Effects and Pharmacokinetics of Cannabidiol: A Scoping Review
por: Matheson, Justin, et al.
Publicado: (2022)

A prospective open‐label trial of a CBD/THC cannabis oil in dravet syndrome
por: McCoy, Bláthnaid, et al.
Publicado: (2018)

Rapid In Situ Detection of THC and CBD in Cannabis sativa L. by 1064 nm Raman Spectroscopy
por: Porcu, Stefania, et al.
Publicado: (2022)

Repeated Exposure to High-THC Cannabis Smoke during Gestation Alters Sex Ratio, Behavior, and Amygdala Gene Expression of Sprague Dawley Rat Offspring
por: Sandini, Thaisa M., et al.
Publicado: (2023)

Glandular trichome development, morphology, and maturation are influenced by plant age and genotype in high THC-containing cannabis (Cannabis sativa L.) inflorescences
por: Punja, Zamir K., et al.
Publicado: (2023)

The impact of cannabis legalization for recreational purposes on youth: A narrative review of the Canadian experience
por: Rubin-Kahana, Dafna Sara, et al.
Publicado: (2022)

Cannabis, Impaired Driving, and Road Safety: An Overview of Key Questions and Issues
por: Brands, Bruna, et al.
Publicado: (2021)

Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition
por: Arkell, Thomas R., et al.
Publicado: (2019)

Direct In Vivo Analysis of CBD- and THC-Acid Cannabinoids and Classification of Cannabis Cultivars Using SpiderMass
por: Ogrinc, Nina, et al.
Publicado: (2022)

THC-Reduced Cannabis sativa L.—How Does the Solvent Determine the Bioavailability of Cannabinoids Given Orally?
por: Bartkowiak-Wieczorek, Joanna, et al.
Publicado: (2023)

Investigating how nitrogen nutrition and pruning impacts on CBD and THC concentration and plant biomass of Cannabis sativa
por: Dilena, Enrico, et al.
Publicado: (2023)

Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios
por: Englund, Amir, et al.
Publicado: (2022)

Delta-8-THC: Delta-9-THC’s nicer younger sibling?
por: Kruger, Jessica S., et al.
Publicado: (2022)

An Exploratory Association Analysis of ABCB(1) rs1045642 and ABCB(1) rs4148738 with Non-Major Bleeding Risk in Atrial Fibrillation Patients Treated with Dabigatran or Apixaban
por: Roşian, Adela-Nicoleta, et al.
Publicado: (2020)

Monitoring the impact of cannabis use
por: Le Foll, Bernard
Publicado: (2022)

Development and validation of an automated liquid-liquid extraction GC/MS method for the determination of THC, 11-OH-THC, and free THC-carboxylic acid (THC-COOH) from blood serum
por: Purschke, Kirsten, et al.
Publicado: (2016)

S222. CLINICAL UTILITY OF PHARMACOGENETIC TESTING IN SCHIZOPHRENIA TREATMENT
por: Mueller, Daniel, et al.
Publicado: (2018)

Antitumor effects of THC.
por: Huff, J, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_rbmpd07fqmip0sff4udg7gb5n5