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The “Yin and Yang” of Unfolded Protein Response in Cancer and Immunogenic Cell Death

Physiological and pathological burdens that perturb endoplasmic reticulum homeostasis activate the unfolded protein response (UPR), a conserved cytosol-to-nucleus signaling pathway that aims to reinstate the vital biosynthetic and secretory capacity of the ER. Disrupted ER homeostasis, causing malad...

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Detalles Bibliográficos
Autores principales: Rufo, Nicole, Yang, Yihan, De Vleeschouwer, Steven, Agostinis, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497201/
https://www.ncbi.nlm.nih.gov/pubmed/36139473
http://dx.doi.org/10.3390/cells11182899