Increased K(V)2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K(+) Currents in Hippocampal Neurons of the Tg2576 Alzheimer’s Disease Mouse

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions. Cortical and hippocampal hyperexcitability intervenes in the pathological derangement of brain activity leading to cognitive decline. As key regulators of neuronal excitabi...

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Detalles Bibliográficos
Autores principales: Piccialli, Ilaria, Sisalli, Maria José, de Rosa, Valeria, Boscia, Francesca, Tedeschi, Valentina, Secondo, Agnese, Pannaccione, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497218/
https://www.ncbi.nlm.nih.gov/pubmed/36139395
http://dx.doi.org/10.3390/cells11182820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497218/
https://www.ncbi.nlm.nih.gov/pubmed/36139395
http://dx.doi.org/10.3390/cells11182820

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