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Increased K(V)2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K(+) Currents in Hippocampal Neurons of the Tg2576 Alzheimer’s Disease Mouse
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions. Cortical and hippocampal hyperexcitability intervenes in the pathological derangement of brain activity leading to cognitive decline. As key regulators of neuronal excitabi...
Autores principales: | Piccialli, Ilaria, Sisalli, Maria José, de Rosa, Valeria, Boscia, Francesca, Tedeschi, Valentina, Secondo, Agnese, Pannaccione, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497218/ https://www.ncbi.nlm.nih.gov/pubmed/36139395 http://dx.doi.org/10.3390/cells11182820 |
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