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Hydrogen Sulfide Attenuates Neuroinflammation by Inhibiting the NLRP3/Caspase-1/GSDMD Pathway in Retina or Brain Neuron following Rat Ischemia/Reperfusion

Gasdermin D-executing pyroptosis mediated by NLRP3 inflammasomes has been recognized as a key pathogenesis during stroke. Hydrogen sulfide (H(2)S) could protect CNS against ischemia/reperfusion (I/R)-induced neuroinflammation, while the underlying mechanism remains unclear. The study applied the mid...

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Detalles Bibliográficos
Autores principales: Yang, Kun-Li, Li, Wen-Hong, Liu, Ya-Jie, Wei, Ying-Juan, Ren, Yan-Kai, Mai, Chen-Di, Zhang, Si-Yu, Zuo, Yue, Sun, Zhen-Zhou, Li, Dong-Liang, Yang, Chih-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497235/
https://www.ncbi.nlm.nih.gov/pubmed/36138981
http://dx.doi.org/10.3390/brainsci12091245