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Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene

SIMPLE SUMMARY: The accumulation of lipid droplets (LDs) and the high expression of genes involved in LD formation, such as SREBF1 (sterol regulatory element binding transcription factor 1), are attributed to cancer cell resistance against anticancer drugs and poor prognosis. We assessed lung cancer...

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Detalles Bibliográficos
Autores principales: Gründing, Anna Ricarda, Schneider, Marc A., Richtmann, Sarah, Kriegsmann, Mark, Winter, Hauke, Martinez-Delgado, Beatriz, Varona, Sarai, Liu, Bin, DeLuca, David S., Held, Julia, Wrenger, Sabine, Muley, Thomas, Meister, Michael, Welte, Tobias, Janciauskiene, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497419/
https://www.ncbi.nlm.nih.gov/pubmed/36139614
http://dx.doi.org/10.3390/cancers14184454