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Effects of Acute Sepsis on Cellular Dynamics and Amyloid Formation in a Mouse Model of Alzheimer’s Disease

Our objective was to investigate how sepsis influences cellular dynamics and amyloid formation before and after plaque formation. As such, APP-mice were subjected to a polymicrobial abdominal infection resulting in sepsis at 2 (EarlySepsis) and 4 (LateSepsis) months of age. Behavior was tested befor...

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Detalles Bibliográficos
Autores principales: Rotaru-Zavaleanu, Alexandra Daniela, Neacșu, Alexandru Ionuț, Neacșu, Adela-Daria, Pirici, Daniel, Osiac, Eugen, Cătălin, Bogdan, Gheonea, Dan Ionuț
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497925/
https://www.ncbi.nlm.nih.gov/pubmed/36135174
http://dx.doi.org/10.3390/cimb44090262