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Oral Lichen Planus and Mutated TP53—A Road to Cancer?

The malignant potential of oral lichen planus (OLP) has been discussed and disputed for decades. The lesions are often characterized by strong expression of the TP53 protein in the basal layer of the mucosa. In 2002, we reported the presence of TP53 mutations in nine out of 27 OLP lesions tested. At...

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Detalles Bibliográficos
Autores principales: Holbrook, William Peter, Ögmundsdottir, Helga M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497945/
https://www.ncbi.nlm.nih.gov/pubmed/36135171
http://dx.doi.org/10.3390/dj10090176