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Direct Targeting of the Raf-MEK-ERK Signaling Cascade Inhibits Neuroblastoma Growth

The Raf-MEK-ERK signaling network has been the subject of intense research due to its role in the development of human cancers, including pediatric neuroblastoma (NB). MEK and ERK are the central components of this signaling pathway and are attractive targets for cancer therapy. Approximately 3–5% o...

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Detalles Bibliográficos
Autores principales: Chilamakuri, Rameswari, Agarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497977/
https://www.ncbi.nlm.nih.gov/pubmed/36135081
http://dx.doi.org/10.3390/curroncol29090512