PADI4 Haplotypes Contribute to mRNA Expression, the Enzymatic Activity of Peptidyl Arginine Deaminase and Rheumatoid Arthritis Risk in Patients from Western Mexico

Citrullination is catalyzed by the peptidyl arginine deiminase 4 (PAD4) enzyme, encoded by the PADI4 gene. Increased PAD4 activity promotes the onset and progression of rheumatoid arthritis (RA). This study aimed to evaluate the association of PADI4 haplotypes with RA risk, mRNA expression, and the...

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Detalles Bibliográficos
Autores principales: Matuz-Flores, Mónica Guadalupe, Rosas-Rodríguez, Jesús Alfredo, Tortoledo-Ortiz, Orlando, Muñoz-Barrios, Salvador, Martínez-Bonilla, Gloria Esther, Hernández-Bello, Jorge, Baños-Hernández, Christian Johana, Pacheco-Tena, Cesar, Sánchez-Zuno, Gabriela Athziri, Panduro-Espinoza, Beatriz, Muñoz-Valle, José Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498032/
https://www.ncbi.nlm.nih.gov/pubmed/36135205
http://dx.doi.org/10.3390/cimb44090293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498032/
https://www.ncbi.nlm.nih.gov/pubmed/36135205
http://dx.doi.org/10.3390/cimb44090293

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