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Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel

Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes. Here, we used a three-dimensional in vitro invasion model consisting of cancer spheroids encapsulated by a ba...

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Detalles Bibliográficos
Autores principales: Nazari, Shayan S., Doyle, Andrew D., Yamada, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498339/
https://www.ncbi.nlm.nih.gov/pubmed/36135279
http://dx.doi.org/10.3390/gels8090567