Cargando…

Senescent Fibroblasts Generate a CAF Phenotype through the Stat3 Pathway

Aging has been recently reported to promote lung cancer initiation and progression. Senescent fibroblasts gain a cancer-associated fibroblast (CAF) phenotype, and exert a powerful influence on cancer behavior, such as tumor cell growth and metastasis. However, mechanisms linking fibroblast senescenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hao, Qiu, Lei, Liu, Qing, Ma, Zelong, Xie, Xiaoli, Luo, Ying, Wu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498467/
https://www.ncbi.nlm.nih.gov/pubmed/36140747
http://dx.doi.org/10.3390/genes13091579