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TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex

Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT). We show that when lncRNA is processed, it gives rise to two abund...

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Detalles Bibliográficos
Autores principales: Polo-Generelo, Salvador, Torres, Belén, Guerrero-Martínez, José A., Camafeita, Emilio, Vázquez, Jesús, Reyes, José C., Pintor-Toro, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498520/
https://www.ncbi.nlm.nih.gov/pubmed/36136852
http://dx.doi.org/10.3390/ncrna8050062