Cargando…

G-quadruplexes Mark Sites of Methylation Instability Associated with Ageing and Cancer

Regulation of the epigenome is critical for healthy cell function but can become disrupted with age, leading to aberrant epigenetic profiles including altered DNA methylation. Recent studies have indicated that DNA methylation homeostasis can be compromised by the formation of DNA secondary structur...

Descripción completa

Detalles Bibliográficos
Autores principales: Rauchhaus, Jonas, Robinson, Jenna, Monti, Ludovica, Di Antonio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498706/
https://www.ncbi.nlm.nih.gov/pubmed/36140833
http://dx.doi.org/10.3390/genes13091665