SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium

Several pathogenic variants have been reported in the IMPG1 gene associated with the inherited retinal disorders vitelliform macular dystrophy (VMD) and retinitis pigmentosa (RP). IMPG1 and its paralog IMPG2 encode for two proteoglycans, SPACR and SPACRCAN, respectively, which are the main component...

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Detalles Bibliográficos
Autores principales: Olivier, Guillaume, Brabet, Philippe, Pirot, Nelly, Broyon, Morgane, Guillou, Laurent, Cazevieille, Chantal, Sar, Chamroeun, Quiles, Melanie, Sarzi, Emmanuelle, Pequignot, Marie, Andreo, Ervann, Roubertie, Agathe, Meunier, Isabelle, Muller, Agnès, Kalatzis, Vasiliki, Manes, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498744/
https://www.ncbi.nlm.nih.gov/pubmed/36140676
http://dx.doi.org/10.3390/genes13091508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498744/
https://www.ncbi.nlm.nih.gov/pubmed/36140676
http://dx.doi.org/10.3390/genes13091508

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