Slow RNAPII Transcription Elongation Rate, Low Levels of RNAPII Pausing, and Elevated Histone H1 Content at Promoters Associate with Higher m6A Deposition on Nascent mRNAs

N6-methyladenosine modification (m6A) fine-tunes RNA fate in a variety of ways, thus regulating multiple fundamental biological processes. m6A writers bind to chromatin and interact with RNA polymerase II (RNAPII) during transcription. To evaluate how the dynamics of the transcription process impact...

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Detalles Bibliográficos
Autores principales: Gallego, Alicia, Fernández-Justel, José Miguel, Martín-Vírgala, Sara, Maslon, Magdalena M., Gómez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498810/
https://www.ncbi.nlm.nih.gov/pubmed/36140819
http://dx.doi.org/10.3390/genes13091652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498810/
https://www.ncbi.nlm.nih.gov/pubmed/36140819
http://dx.doi.org/10.3390/genes13091652

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